A 23-year-old driver has died and his passenger seriously injured after the car they were in crashed.
The accident involved one car, a white Honda CRX, which left the road at 10.15pm on the A709 Lochmaben to Lockerbie road, near Lochmaben.
The driver, a local man, died at the scene while his 21-year-old passenger, also local, was taken to Dumfries and Galloway Infirmary in a serious condition.
The road was closed for several hours while crash scene investigations were carried out. It was reopened at 4.50am.
A police spokesman said: "The collision involved one vehicle, a white Honda CRX, and occurred at around 22.15 on Wednesday 30 January. The vehicle was being driven by a local 23-year-old man who died at the scene as a result of injuries sustained.
"A 21-year-old local male passenger sustained serious injuries in the collision and was taken to DGRI to receive treatment. His current condition is described as serious but stable."
Police are appealing for anyone who was in the area at the time, or who saw the car before the crash, to call them on 0845 600 5701 or Crimestoppers anonymously on 0800 555 111.